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Interferon gamma 抗体 (APC)

This anti-Interferon gamma antibody is a 小鼠 单克隆 antibody detecting Interferon gamma in FACS 和 IF. Suitable for 人.
产品编号 ABIN1107655
发货至: 中国

Quick Overview for Interferon gamma 抗体 (APC) (ABIN1107655)

抗原

See all Interferon gamma (IFNG) 抗体
Interferon gamma (IFNG)

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This Interferon gamma antibody is conjugated to APC

应用范围

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Flow Cytometry (FACS), Immunofluorescence (IF)

克隆位点

45-14
  • 特异性

    The antibody detects human IFN-gamma, a 20-25 kDa glycoprotein expressed by subsets of T cells and NK cells, that have been stimulated by antigens or mitogens (1-4). Other species not tested.

    纯化方法

    Affinity chromatography

    亚型

    IgG1
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 缓冲液

    0.01 M sodium phosphate, 0.15 M NaCl, pH 7.3, 0.2 % BSA, 0.09 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Store the antibody undiluted at 2-8 °C. Fluorochrome labelled product is photosensitive and should be protected from light.
  • 抗原

    Interferon gamma (IFNG)

    别名

    IFNG / Interferon gamma

    背景

    The immune system reacts to a pathogen by activation of balanced network of the humoral and cellular immune responses. Subsequently the activated condition of the immune system will, after the elimination of the pathogen, be down-regulated to a balanced situation again. Control of the immune response requires efficient communication between the different cells involved in this response. This interaction is provided by cell/cell contact and by a complex array of mediators. Among these mediators cytokines, soluble factors produced by these cells, play an important role. Cytokines can act on other cells locally or distantly, but can be even auto regulating. Cytokines can behave stimulatory or inhibitory, or can even perform both activities, depending on the (pre)activation stage of the target cell. (3, 4) IFN-gamma has antiviral activity and multiple immunoregulatory functions such as upregulation of MHCClass I antigens on monocytes/macrophages and specific adhesion molecules (e.g. ICAM1 and VCAM1) on endothelial cells. IFN-gamma enhances IgG production by activated B cells, displays chemotactic activities, and plays a role in induction of inflammation.Synonyms: IFN-gamma, gamma IFN

    基因ID

    3458

    NCBI登录号

    NP_000610

    UniProt

    P01579

    途径

    Interferon-gamma Pathway, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, ER-Nucleus Signaling, Regulation of Carbohydrate Metabolic Process, Protein targeting to Nucleus, Autophagy
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